Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDT | P30046 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3767934 | 0.99 | DDT (0.38) | DDTPTPN11AXLPTGER1CYP2C9 | |
| SCHEMBL3137115 | 0.89 | FFAR4 (0.41) | MAP4K4 | |
| Hydrochloric Acid SCHEMBL3782911 | 0.88 | DDT (0.39) | DDTPTPN11AXLPTGER1EIF4EBP1 | |
| SCHEMBL3155954 | 0.86 | FFAR4 (0.40) | — | |
| Hydrochloric Acid SCHEMBL3151269 | 0.83 | FYN (0.40) | — | |
| SCHEMBL4761397 | 0.83 | CYP1A2 (0.38) | CYP2C9CYP3A4 | |
| SCHEMBL3155310 | 0.82 | ABL1 (0.41) | CYP3A4 | |
| Hydrochloric Acid SCHEMBL3777918 | 0.81 | KMO (0.44) | — | |
| SCHEMBL3143075 | 0.81 | CHEK2 (0.39) | MAP4K4 | |
| Hydrochloric Acid SCHEMBL3774096 | 0.81 | FNTA (0.40) | DDTAXLPTGER1MAP4K4EIF4EBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979321-B9 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2010-02-17 | — | — | EP | disclosed |
| EP-1979321-B1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2009-07-29 | — | — | EP | disclosed |
| EP-1979321-A1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Les Laboratoires Servier (FR) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007085750-A1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2007-08-02 | — | — | WO | disclosed |