Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 4/20 | 0.58 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.58 |
| ▸ | KHK | P50053 | 8/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | C1S | P09871 | 3/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23538689 | 0.91 | DDB1 (0.68) | DDB1CRBNKHKHTR6HTR1A | |
| Hydrochloric Acid SCHEMBL28995428 | 0.90 | DDB1 (0.67) | DDB1CRBNKHKHTR6HTR1A | |
| Trifluoroacetic Acid SCHEMBL38657629 | 0.90 | DDB1 (0.57) | DDB1CRBNKHKHTR6C1S | |
| Trifluoroacetic Acid SCHEMBL30915064 | 0.88 | DDB1 (0.57) | DDB1CRBNKHKC1S | |
| SCHEMBL31323432 | 0.85 | DDB1 (0.65) | DDB1CRBNKHKHTR6HTR1A | |
| Trifluoroacetic Acid SCHEMBL31458443 | 0.84 | DDB1 (0.49) | DDB1CRBN | |
| Trifluoroacetic Acid SCHEMBL29641005 | 0.84 | DDB1 (0.56) | DDB1CRBNKHKHTR1A | |
| SCHEMBL23538921 | 0.84 | DDB1 (0.63) | DDB1CRBNKHK | |
| SCHEMBL24873284 | 0.82 | DDB1 (0.69) | DDB1CRBNKHKHTR6 | |
| SCHEMBL23538519 | 0.82 | CRBN (0.69) | DDB1CRBNKHKHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067509-A1 | EGFR DEGRADANT, AND PREPARATION METHOD AND USE THEREFOR | 石药集团中奇制药技术（石家庄）有限公司 | 2025-04-03 | — | — | WO | disclosed |