SCHEMBL31458723

SCHEMBL31458723

C[C@H](CC(=O)N(c1cc(C(=O)NCC(F)(F)F)nn1C)[C@@H]1C(=O)N2CCCN2Cc2ccccc21)C(N)=O

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ SPPL2A Q8TCT8 14/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31458741 0.86 SPPL2A (0.47) SPPL2A
SCHEMBL31458773 0.81 SPPL2A (0.44) SPPL2A
SCHEMBL31458734 0.80 SPPL2A (0.46) SPPL2A
SCHEMBL26854641 0.76 SPPL2A (0.84) SPPL2A
SCHEMBL31458742 0.72 SPPL2A (0.46) SPPL2A
SCHEMBL26854881 0.70 SPPL2A (0.81) SPPL2A
SCHEMBL26848225 0.68 SPPL2A (1.00) SPPL2A
SCHEMBL31458660 0.67 SPPL2A (0.39) SPPL2A
SCHEMBL26855281 0.65 SPPL2A (0.81) SPPL2A
SCHEMBL30617016 0.64 SPPL2A (0.79) SPPL2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4214210-B1 COMPOUNDS AND COMPOSITIONS AS SPPL2A INHIBITORS NOVARTIS AG (CH) 2025-04-09 — — EP disclosed
Send feedback