Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPPL2A | Q8TCT8 | 14/20 | 0.46 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31458741 | 0.82 | SPPL2A (0.47) | SPPL2A | |
| SCHEMBL31458723 | 0.80 | SPPL2A (0.51) | SPPL2A | |
| SCHEMBL26848245 | 0.78 | SPPL2A (0.77) | SPPL2A | |
| SCHEMBL31458773 | 0.73 | SPPL2A (0.44) | SPPL2A | |
| SCHEMBL26848229 | 0.73 | SPPL2A (0.80) | SPPL2A | |
| SCHEMBL31458742 | 0.70 | SPPL2A (0.46) | SPPL2A | |
| SCHEMBL31458660 | 0.65 | SPPL2A (0.39) | SPPL2A | |
| SCHEMBL26854539 | 0.64 | SPPL2A (1.00) | SPPL2A | |
| SCHEMBL26855731 | 0.63 | SPPL2A (0.79) | SPPL2A | |
| SCHEMBL26848232 | 0.62 | SPPL2A (0.81) | SPPL2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214210-B1 | COMPOUNDS AND COMPOSITIONS AS SPPL2A INHIBITORS | NOVARTIS AG (CH) | 2025-04-09 | — | — | EP | disclosed |