SCHEMBL31458897

SCHEMBL31458897

CCOc1cc(C2(c3nncn3C(F)F)CC(C)C2)cc(Cl)n1

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 8/20 0.39
▸ CBL P22681 6/20 0.32
▸ S1PR2 O95136 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31274922 0.86 CBLB (0.47) CBLBCBL
SCHEMBL31459392 0.81 CBLB (0.41) CBLBCBL
SCHEMBL31275333 0.79 CBLB (0.35) CBLBS1PR2
SCHEMBL31549955 0.79 CBLB (0.42) CBLBCBL
SCHEMBL31459162 0.74 CBLB (0.32) CBLBS1PR2
SCHEMBL31251387 0.74 CBLB (0.46) CBLBCBL
SCHEMBL31458873 0.74 CBLB (0.44) CBLBCBL
SCHEMBL31458946 0.72 — —
SCHEMBL25183563 0.72 CBLB (0.36) CBLB
SCHEMBL25413016 0.71 CBLB (0.48) CBLBCBL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025067227-A1 PREPARATION METHOD FOR CBL-B REGULATOR, AND USE 浙江华海药业股份有限公司 2025-04-03 — — WO disclosed
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