Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 5/20 | 0.31 |
| ▸ | PLK4 | O00444 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | ROS1 | P08922 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | FRK | P42685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31459414 | 0.86 | AR (0.31) | AR | |
| SCHEMBL31459341 | 0.78 | ROCK1 (0.36) | GRM2KDRPLK4ROCK2NTRK1 | |
| SCHEMBL31459326 | 0.75 | HTR2A (0.33) | HTR2AHTR2CHTR2BAR | |
| SCHEMBL31459127 | 0.75 | AR (0.31) | AR | |
| SCHEMBL31458961 | 0.72 | CBLB (0.38) | — | |
| SCHEMBL27086006 | 0.71 | GRM2 (0.47) | GRM2PIK3CDPIK3CAPIK3CBKDR | |
| SCHEMBL29841781 | 0.71 | HTR2A (0.38) | GRM2HTR2AHTR2CHTR2BPIK3CD | |
| SCHEMBL21200175 | 0.71 | HTR2A (0.38) | GRM2HTR2AHTR2CHTR2BPIK3CD | |
| SCHEMBL25412815 | 0.68 | GRM2 (0.35) | GRM2PIK3CDPIK3CAPIK3CBKDR | |
| SCHEMBL31159152 | 0.66 | GRM5 (0.36) | HTR2AHTR2CHTR2BPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067227-A1 | PREPARATION METHOD FOR CBL-B REGULATOR, AND USE | 浙江华海药业股份有限公司 | 2025-04-03 | — | — | WO | disclosed |