Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.31 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.31 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.31 |
| ▸ | PLK4 | O00444 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31459127 | 0.79 | AR (0.31) | AR | |
| SCHEMBL31459326 | 0.79 | HTR2A (0.33) | AR | |
| SCHEMBL31459263 | 0.78 | GRM2 (0.33) | ROCK1ARKDRPLK4ROCK2 | |
| SCHEMBL31459414 | 0.78 | AR (0.31) | AR | |
| SCHEMBL29514638 | 0.71 | ROCK1 (0.41) | ROCK1PIM1CSNK1A1CDK5DYRK1A | |
| SCHEMBL21200262 | 0.71 | ROCK1 (0.41) | ROCK1PIM1CSNK1A1CDK5DYRK1A | |
| SCHEMBL27086145 | 0.68 | CLK4 (0.49) | ROCK1PIM1CSNK1A1CDK5DYRK1A | |
| SCHEMBL31159152 | 0.66 | GRM5 (0.36) | ROCK1PIM1CLK4ARKDR | |
| SCHEMBL22663398 | 0.65 | PIM1 (0.49) | ROCK1PIM1CSNK1A1CDK5DYRK1A | |
| SCHEMBL25186469 | 0.65 | HTR2A (0.38) | ROCK1PIM1CSNK1A1CDK5DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067227-A1 | PREPARATION METHOD FOR CBL-B REGULATOR, AND USE | 浙江华海药业股份有限公司 | 2025-04-03 | — | — | WO | disclosed |