Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.38 |
| ▸ | F12 | P00748 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | ACR | P10323 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | C1R | P00736 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31460485 | 0.91 | MMP9 (0.47) | GRM5MAPTKMT2AMEN1HSD17B10 | |
| Hydrochloric Acid SCHEMBL31460229 | 0.89 | MAPT (0.47) | MAPTKMT2AMEN1HSD17B10GAA | |
| Hydrochloric Acid SCHEMBL31460351 | 0.84 | MAPK14 (0.41) | GRM5MAPTKMT2AMEN1HSD17B10 | |
| SCHEMBL16995901 | 0.83 | GRM5 (0.47) | GRM5MAPTKMT2AMEN1HSD17B10 | |
| Hydrochloric Acid SCHEMBL31460428 | 0.83 | BAZ2B (0.47) | GRM5MAOAMAOBPRSS1F12 | |
| SCHEMBL31460423 | 0.82 | PRSS1 (0.44) | GRM5KMT2AMEN1PRSS1F12 | |
| SCHEMBL31460459 | 0.79 | PRSS1 (0.43) | MAPTKMT2AMEN1MAOAPRSS1 | |
| Hydrochloric Acid SCHEMBL31460358 | 0.78 | PLAU (0.48) | MAPTKMT2AMEN1CA12CA1 | |
| Hydrochloric Acid SCHEMBL31460337 | 0.78 | PLAU (0.51) | MAPTKMT2AMEN1CA12CA1 | |
| SCHEMBL10956570 | 0.77 | KMT2A (0.56) | MAPTKMT2AMEN1HSD17B10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371391-A | Aroyl compound and preparation method and application thereof | 河北医科大学 | 2025-01-28 | — | — | CN | disclosed |