Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 5/20 | 0.44 |
| ▸ | F12 | P00748 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 5/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | C1R | P00736 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | KLK1 | P06870 | 2/20 | 0.41 |
| ▸ | F11 | P03951 | 3/20 | 0.40 |
| ▸ | PLG | P00747 | 2/20 | 0.39 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | ACR | P10323 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31460423 | 0.92 | PRSS1 (0.44) | PRSS1F12PRSS2PRSS3PARP10 | |
| SCHEMBL31460459 | 0.83 | PRSS1 (0.43) | PRSS1F12PRSS2PRSS3KLKB1 | |
| SCHEMBL31460485 | 0.82 | MMP9 (0.47) | PRSS1F12PRSS2PRSS3F2 | |
| SCHEMBL28724678 | 0.80 | PARP10 (0.53) | PARP1PARP10F7F3MAPKAPK2 | |
| Hydrochloric Acid SCHEMBL31460490 | 0.79 | KMT2A (0.50) | PRSS1F12PRSS2PRSS3ACR | |
| Hydrochloric Acid SCHEMBL31460396 | 0.78 | PARP10 (0.40) | PRSS1F12PRSS2PRSS3PARP10 | |
| Hydrochloric Acid SCHEMBL31460337 | 0.78 | PLAU (0.51) | PRSS1F12PRSS2PRSS3PLAU | |
| Hydrochloric Acid SCHEMBL31460358 | 0.78 | PLAU (0.48) | PRSS1F12PRSS2PRSS3PLAU | |
| Hydrochloric Acid SCHEMBL31460357 | 0.77 | CRBN (0.47) | PRSS1F12PRSS2PRSS3ACR | |
| Hydrochloric Acid SCHEMBL31460351 | 0.77 | MAPK14 (0.41) | PRSS1F12PRSS2PRSS3KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371391-A | Aroyl compound and preparation method and application thereof | 河北医科大学 | 2025-01-28 | — | — | CN | disclosed |