Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | AR | P10275 | 4/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3774537 | 0.99 | KDM1A (0.39) | KDM1AARCYP11B2EGLN1P2RX7 | |
| SCHEMBL3151084 | 0.87 | CHRNB4 (0.40) | KDM4E | |
| Hydrochloric Acid SCHEMBL3779005 | 0.86 | CHRNB4 (0.39) | KDM4E | |
| SCHEMBL3141366 | 0.85 | SYK (0.37) | — | |
| SCHEMBL3142559 | 0.84 | PIK3CD (0.34) | CYP11B2 | |
| SCHEMBL3151443 | 0.80 | KDM1A (0.43) | KDM1A | |
| Hydrochloric Acid SCHEMBL3779588 | 0.79 | KDM1A (0.42) | KDM1A | |
| SCHEMBL3146697 | 0.79 | ABL1 (0.39) | — | |
| SCHEMBL3152381 | 0.79 | AR (0.38) | KDM1AAREGLN1P2RX7EGLN2 | |
| SCHEMBL3152373 | 0.78 | EGLN1 (0.41) | KDM1AAREGLN1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979321-B9 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2010-02-17 | — | — | EP | disclosed |
| EP-1979321-B1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2009-07-29 | — | — | EP | disclosed |