Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | CLK1 | P49759 | 7/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3775074 | 0.99 | ABL1 (0.38) | ABL1CYP2A6CLK1DYRK1AMCHR1 | |
| SCHEMBL3151084 | 0.83 | CHRNB4 (0.40) | — | |
| Hydrochloric Acid SCHEMBL3779005 | 0.82 | CHRNB4 (0.39) | — | |
| SCHEMBL3141366 | 0.81 | SYK (0.37) | CLK1DYRK1A | |
| Hydrochloric Acid SCHEMBL3778971 | 0.81 | SYK (0.36) | CLK1DYRK1A | |
| SCHEMBL3155310 | 0.80 | ABL1 (0.41) | ABL1 | |
| SCHEMBL3142555 | 0.79 | ABL1 (0.39) | ABL1CLK1DYRK1AMCHR1 | |
| SCHEMBL3146047 | 0.79 | KDM1A (0.40) | — | |
| SCHEMBL3142552 | 0.78 | ABL1 (0.41) | ABL1MCHR1 | |
| Hydrochloric Acid SCHEMBL3774537 | 0.78 | KDM1A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979321-B9 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2010-02-17 | — | — | EP | disclosed |
| EP-1979321-B1 | NOVEL PYRIDINYLAMINOALKYLENE- AND PYRIDINYLOXYALKYLENE-CYCLOPROPANAMINES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2009-07-29 | — | — | EP | disclosed |