Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 5/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | USP14 | P54578 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13255982 | 0.87 | CTSK (0.54) | CTSKKCNA3CA1CA2DRD2 | |
| SCHEMBL2299641 | 0.84 | CTSK (0.51) | CTSKKCNA3CA1CA2DRD2 | |
| SCHEMBL17108791 | 0.84 | CTSK (0.51) | CTSKKCNA3CA1CA2DRD2 | |
| SCHEMBL3965693 | 0.82 | CTSK (0.55) | CTSKKCNA3CA1CA2DRD2 | |
| SCHEMBL27460572 | 0.82 | CTSK (0.55) | CTSKKCNA3CA1CA2DRD2 | |
| SCHEMBL7586943 | 0.81 | CTSK (0.51) | CTSKKCNA3CA1CA2DRD2 | |
| SCHEMBL26785048 | 0.81 | CTSK (0.54) | CTSKKCNA3CA1CA2DRD2 | |
| SCHEMBL18658256 | 0.81 | CTSK (0.54) | CTSKKCNA3CA1CA2DRD2 | |
| SCHEMBL1525518 | 0.81 | CTSK (0.57) | CTSKKCNA3CA1CA2DRD2 | |
| SCHEMBL3115202 | 0.80 | KCNA3 (0.55) | CTSKKCNA3CA1CA2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076441-A1 | COMPOUNDS OF GCN2 MODULATORS | Alesta Therapeutics BV (NL) | 2025-04-10 | — | — | WO | disclosed |