Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | CASP3 | P42574 | 2/20 | 0.64 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.64 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.64 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.63 |
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23850845 | 1.00 | POLB (0.67) | POLBNPC1RAB9ACASP3SENP8 | |
| SCHEMBL31461247 | 0.84 | POLB (0.77) | POLBNPC1RAB9ACASP3SENP8 | |
| SCHEMBL23850835 | 0.84 | POLB (0.77) | POLBNPC1RAB9ACASP3SENP8 | |
| SCHEMBL6320632 | 0.81 | POLB (1.00) | POLBNPC1RAB9ACASP3SENP8 | |
| SCHEMBL107774 | 0.80 | MAOB (1.00) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL29382160 | 0.80 | MAOB (1.00) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL29547560 | 0.77 | NPC1 (0.76) | POLBNPC1RAB9ACASP3SENP8 | |
| SCHEMBL23012727 | 0.77 | NPC1 (0.76) | POLBNPC1RAB9ACASP3SENP8 | |
| SCHEMBL23012450 | 0.75 | MEN1 (0.74) | POLBNPC1RAB9ACASP3SENP8 | |
| SCHEMBL29547915 | 0.75 | MEN1 (0.74) | POLBNPC1RAB9ACASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113347965-B | TGF-beta inhibitors and prodrugs | 生物医学研究机构基金会 | 2025-02-18 | — | — | CN | disclosed |