Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.84 |
| ▸ | MEN1 | O00255 | 3/20 | 0.84 |
| ▸ | NPC1 | O15118 | 3/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.72 |
| ▸ | MAPT | P10636 | 8/20 | 0.72 |
| ▸ | HPGD | P15428 | 5/20 | 0.72 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.72 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | CASP3 | P42574 | 1/20 | 0.67 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.67 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.67 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.67 |
| ▸ | AR | P10275 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31461247 | 0.87 | POLB (0.77) | POLBKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL23850835 | 0.87 | POLB (0.77) | POLBKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL15499731 | 0.83 | ALDH1A1 (0.81) | POLBKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL2803955 | 0.82 | ALDH1A1 (0.80) | POLBKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL29881770 | 0.82 | ALDH1A1 (0.80) | POLBKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL11316690 | 0.82 | AR (0.74) | POLBKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL4386227 | 0.81 | KDM4E (0.79) | POLBKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL3210418 | 0.81 | ALDH1A1 (0.79) | POLBKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL5717615 | 0.81 | AR (0.73) | POLBKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL23850845 | 0.81 | POLB (0.67) | POLBKMT2AMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |