Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | DDX3X | O00571 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23623650 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL31461719 | 0.84 | HDAC3 (0.47) | HPGDSMN1; SMN2RAB9AALDH1A1KDM4E | |
| SCHEMBL23623812 | 0.84 | HPGD (0.46) | HPGDSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL31461684 | 0.82 | SMN1; SMN2 (0.42) | HPGDSMN1; SMN2RAB9AKDM4EHTT | |
| SCHEMBL31461683 | 0.82 | SMN1; SMN2 (0.42) | HPGDSMN1; SMN2RAB9AKDM4EHTT | |
| SCHEMBL23623348 | 0.79 | ALDH1A1 (0.46) | HPGDSMN1; SMN2KMT2AMEN1RAB9A | |
| SCHEMBL23623561 | 0.79 | TP53 (0.46) | HPGDSMN1; SMN2ALDH1A1HTTMAPT | |
| SCHEMBL23623286 | 0.79 | KMT2A (0.47) | HPGDSMN1; SMN2KMT2AMEN1RAB9A | |
| SCHEMBL24177602 | 0.78 | POLB (0.47) | HPGDSMN1; SMN2ALDH1A1MAPTMAPK1 | |
| SCHEMBL23623252 | 0.78 | TSHR (0.43) | HPGDSMN1; SMN2KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024543-A1 | TRICYCLIC UBE2K MODULATORS AND METHODS FOR THEIR USE | BPGBIO, INC. (US) | 2025-01-30 | — | — | WO | disclosed |