Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 8/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31461712 | 1.00 | RORC (0.80) | RORCALDH1A1GAARAB9AKDM4E | |
| SCHEMBL31461740 | 1.00 | RORC (0.80) | RORCALDH1A1GAARAB9AKDM4E | |
| SCHEMBL31461725 | 0.93 | RORC (0.80) | RORCALDH1A1GAARAB9AKDM4E | |
| SCHEMBL31461729 | 0.93 | RORC (0.80) | RORCALDH1A1GAARAB9AKDM4E | |
| SCHEMBL31461722 | 0.93 | RORC (0.80) | RORCALDH1A1GAARAB9AKDM4E | |
| SCHEMBL23850164 | 0.89 | RORC (1.00) | RORCALDH1A1GAARAB9AKDM4E | |
| SCHEMBL31461666 | 0.89 | RORC (1.00) | RORCALDH1A1GAARAB9AKDM4E | |
| SCHEMBL31461723 | 0.87 | RORC (0.61) | RORCALDH1A1GAAMAPTMEN1 | |
| SCHEMBL31461703 | 0.84 | RORC (0.79) | RORCALDH1A1GAARAB9AKDM4E | |
| SCHEMBL31461739 | 0.84 | RORC (0.79) | RORCALDH1A1GAARAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025097247-A1 | METHOD OF TREATMENT OF FIBROSIS WITH INVERSE AGONIST OF RAR RELATED ORPHAN RECEPTORS (RORS) | 11949098 CANADA INC. (CA) | 2025-05-15 | — | — | WO | claimed |
| WO-2025097247-A1 | METHOD OF TREATMENT OF FIBROSIS WITH INVERSE AGONIST OF RAR RELATED ORPHAN RECEPTORS (RORS) | 11949098 CANADA INC. (CA) | 2025-05-15 | — | — | WO | disclosed |