SCHEMBL31462935

SCHEMBL31462935

CO[C@@H]1[C@H](OP(=O)(O)O)[C@@H](C)O[C@H]1n1cnc2c(=O)[nH]c(N)nc21

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ NT5E P21589 1/20 0.51
▸ TAS1R3 Q7RTX0 1/20 0.49
▸ TAS1R1 Q7RTX1 1/20 0.49
▸ FUT5 Q11128 1/20 0.48
▸ STING1 Q86WV6 5/20 0.48
▸ TGM2 P21980 1/20 0.47
▸ HPGD P15428 1/20 0.47
▸ HINT1 P49773 1/20 0.47
▸ POLB P06746 1/20 0.46
▸ PDE3B Q13370 1/20 0.46
▸ PDE3A Q14432 1/20 0.46
▸ IMPDH2 P12268 1/20 0.46
▸ IMPDH1 P20839 1/20 0.46
▸ HPRT1 P00492 1/20 0.46
▸ PNP P00491 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2218829 0.90 HPGD (0.57) NT5ETAS1R3TAS1R1FUT5TGM2
SCHEMBL21344309 0.90 NT5E (0.55) NT5ETAS1R3TAS1R1FUT5TGM2
SCHEMBL888070 0.90 HPGD (0.57) NT5ETAS1R3TAS1R1FUT5TGM2
SCHEMBL1299533 0.89 NT5E (0.58) NT5ETAS1R3TAS1R1FUT5STING1
SCHEMBL1299520 0.89 NT5E (0.58) NT5ETAS1R3TAS1R1FUT5STING1
SCHEMBL17438077 0.86 HPGD (0.57) NT5ETAS1R3TAS1R1FUT5TGM2
SCHEMBL17461707 0.83 NT5E (0.54) NT5ETAS1R3TAS1R1FUT5TGM2
SCHEMBL15832464 0.83 HPGD (0.56) NT5ETAS1R3TAS1R1FUT5TGM2
SCHEMBL12590073 0.83 NT5E (0.53) NT5ETAS1R3TAS1R1FUT5TGM2
SCHEMBL33190 0.83 NT5E (0.53) NT5ETAS1R3TAS1R1FUT5TGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120020252-A SiRNA for inhibiting LPA expression and application thereof 纳肽得(青岛)生物医药有限公司 2025-05-20 — — CN disclosed
CN-120005877-A SiRNA for inhibiting expression of complement factor B and application thereof 纳肽得(青岛)生物医药有限公司 2025-05-16 — — CN disclosed
CN-120005876-A SiRNA for inhibiting expression of angiotensinogen and application thereof 纳肽得(青岛)生物医药有限公司 2025-05-16 — — CN disclosed
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