Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29110419 | 0.81 | POLB (0.77) | NPC1MAPTPOLBESR1ESR2 | |
| SCHEMBL30089877 | 0.79 | MAPT (0.69) | NPC1MEN1KMT2ATP53MAPT | |
| SCHEMBL30089869 | 0.79 | POLB (0.73) | NPC1MAPTPOLBESR1ESR2 | |
| SCHEMBL29110416 | 0.79 | POLB (0.58) | NPC1MAPTPOLBESR1ESR2 | |
| SCHEMBL31463104 | 0.79 | NPC1 (0.71) | NPC1MAPTPOLBESR1ESR2 | |
| SCHEMBL29110444 | 0.79 | MAPT (0.69) | NPC1MEN1KMT2ATP53MAPT | |
| SCHEMBL30089874 | 0.79 | MAPT (0.69) | NPC1MEN1KMT2ATP53MAPT | |
| SCHEMBL29110427 | 0.79 | POLB (0.73) | NPC1MAPTPOLBESR1ESR2 | |
| SCHEMBL29110461 | 0.77 | HRH3 (0.63) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL5863341 | 0.76 | LMNA (0.61) | NPC1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954731-A | Chalcone derivative containing 4-quinazolinone structure, and preparation method and application thereof | 黔南州烟草公司平塘县分公司 | 2025-05-09 | — | — | CN | disclosed |