SCHEMBL31463589

SCHEMBL31463589

COC(=O)c1ccc(NC(=O)c2ccc(I)cc2N2CCC3(CC2)CC3)cc1N1CCC(F)(F)CC1

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31463561 0.89 KIF18A (0.56) KIF18A
SCHEMBL31346971 0.87 KIF18A (0.49) KIF18A
SCHEMBL26151578 0.87 KIF18A (0.52) KIF18A
SCHEMBL26151446 0.87 KIF18A (0.52) KIF18A
SCHEMBL31463507 0.86 KIF18A (0.50) KIF18A
SCHEMBL29578579 0.85 MEN1 (0.40) KIF18A
SCHEMBL22964565 0.85 MEN1 (0.40) KIF18A
SCHEMBL26151425 0.85 KIF18A (0.55) KIF18A
SCHEMBL31463568 0.85 KIF18A (0.68) KIF18A
SCHEMBL26151703 0.85 KIF18A (0.51) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748837-A1 AROMATIC AMIDE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Hisun Pharmaceutical Co., Ltd. (CN) 2026-05-27 — — EP disclosed
WO-2025021003-A1 AROMATIC AMIDE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 浙江海正药业股份有限公司 2025-01-30 — — WO disclosed
Send feedback