Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5253912 | 0.90 | TP53 (0.46) | GAATSHRALDH1A1MAPK1CYP2C19 | |
| SCHEMBL31463762 | 0.85 | CHRM2 (0.40) | GAATSHRMAPK1CHRM2MEN1 | |
| SCHEMBL31463823 | 0.81 | CHRM2 (0.37) | GAATSHRALDH1A1CYP2C19CHRM2 | |
| SCHEMBL31463674 | 0.81 | CHRM2 (0.37) | GAATSHRCHRM2MEN1KMT2A | |
| SCHEMBL3134779 | 0.79 | TP53 (0.53) | TSHRALDH1A1CHRM2MEN1KMT2A | |
| SCHEMBL791338 | 0.79 | TSHR (0.45) | GAATSHRALDH1A1MAPK1CYP2C19 | |
| SCHEMBL19596732 | 0.77 | TSHR (0.44) | GAATSHRALDH1A1MAPK1CYP2C19 | |
| SCHEMBL17851396 | 0.77 | TSHR (0.44) | GAATSHRALDH1A1MAPK1CYP2C19 | |
| SCHEMBL13003548 | 0.75 | SMN1; SMN2 (0.63) | ALDH1A1MEN1KMT2ACYP2D6POLB | |
| SCHEMBL21938016 | 0.75 | TP53 (0.45) | GAATSHRALDH1A1MAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024707-A1 | INHIBITORS OF CDK2/4/6 KINASE | KINNATE BIOPHARMA INC. (US) | 2025-01-30 | — | — | WO | disclosed |