Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31463669 | 0.81 | GAA (0.48) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL31463762 | 0.80 | CHRM2 (0.40) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL31463823 | 0.79 | CHRM2 (0.37) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL31463763 | 0.73 | AKR1C3 (0.40) | MEN1KMT2ASMN1; SMN2TSHRLMNA | |
| SCHEMBL5253912 | 0.71 | TP53 (0.46) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL13003548 | 0.71 | SMN1; SMN2 (0.63) | CYP2D6MEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL13910098 | 0.69 | SMN1; SMN2 (0.41) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL31263566 | 0.69 | ALOX5AP (0.34) | TSHRCA1CA2 | |
| SCHEMBL31263468 | 0.69 | ALOX5AP (0.34) | TSHRCA1CA2 | |
| SCHEMBL25153263 | 0.67 | CYP3A4 (0.57) | CHRM2CHRM1CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024707-A1 | INHIBITORS OF CDK2/4/6 KINASE | KINNATE BIOPHARMA INC. (US) | 2025-01-30 | — | — | WO | disclosed |