Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.59 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.47 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.47 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.47 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.47 |
| ▸ | KCNN3 | Q9UGI6 | 12/20 | 0.41 |
| ▸ | KCNN1 | Q92952 | 2/20 | 0.41 |
| ▸ | KCNN2 | Q9H2S1 | 2/20 | 0.41 |
| ▸ | CDK7 | P50613 | 2/20 | 0.36 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCNH | P51946 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434807 | 0.98 | PDE10A (0.61) | PDE10APRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL12953048 | 0.85 | PDE10A (0.57) | PDE10APRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL7003416 | 0.83 | PDE10A (0.54) | PDE10APRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL7836134 | 0.81 | PDE10A (0.53) | PDE10APRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL7829913 | 0.81 | PDE10A (0.53) | PDE10APRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL14679357 | 0.81 | PDE10A (0.61) | PDE10APRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL12953878 | 0.81 | PDE10A (0.56) | PDE10APRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL13288401 | 0.80 | PDE10A (0.51) | PDE10APRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL11608751 | 0.79 | PRKAB2 (0.49) | PDE10APRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL17690933 | 0.79 | PRKAB2 (0.49) | PDE10APRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025068090-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2025-04-03 | — | — | WO | disclosed |