Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 16/20 | 0.38 |
| ▸ | CDK9 | P50750 | 16/20 | 0.38 |
| ▸ | CDK4 | P11802 | 4/20 | 0.38 |
| ▸ | CCND1 | P24385 | 4/20 | 0.38 |
| ▸ | CDK7 | P50613 | 4/20 | 0.38 |
| ▸ | CCNH | P51946 | 4/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | CCNK | O75909 | 1/20 | 0.34 |
| ▸ | CDK14 | O94921 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26874533 | 0.83 | CCNT1 (0.53) | CDK2CCNA1CCNA2CCNT1CDK9 | |
| SCHEMBL17787567 | 0.81 | CCNT1 (0.43) | CDK2CCNA1CCNA2CHEK1PDE10A | |
| SCHEMBL31465378 | 0.81 | PDE10A (0.41) | CDK2CCNA1CCNA2PDE10ACCNT1 | |
| SCHEMBL31465383 | 0.81 | PDE10A (0.41) | CDK2CCNA1CCNA2PDE10ACCNT1 | |
| SCHEMBL26872947 | 0.79 | CCNA2 (0.47) | CDK2CCNA1CCNA2CHEK1CCNT1 | |
| SCHEMBL26873181 | 0.79 | CCNT1 (0.47) | CDK2CCNA1CCNA2CHEK1CCNT1 | |
| SCHEMBL26873161 | 0.79 | CCNT1 (0.47) | CDK2CCNA1CCNA2CHEK1CCNT1 | |
| SCHEMBL26872928 | 0.79 | CCNT1 (0.47) | CDK2CCNA1CCNA2CHEK1CCNT1 | |
| SCHEMBL31465470 | 0.79 | PDE10A (0.61) | PDE10ACCNT1CDK9CDK4CCND1 | |
| SCHEMBL26874521 | 0.79 | CCNT1 (0.53) | CDK2CCNA1CCNA2CHEK1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025068090-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2025-04-03 | — | — | WO | disclosed |