Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 15/20 | 0.39 |
| ▸ | CDK9 | P50750 | 15/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 3/20 | 0.36 |
| ▸ | CCNH | P51946 | 3/20 | 0.36 |
| ▸ | CDK4 | P11802 | 3/20 | 0.36 |
| ▸ | CCND1 | P24385 | 3/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.35 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.34 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.34 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31465383 | 1.00 | PDE10A (0.41) | PDE10ACCNT1CDK9PIK3CGPDE2A | |
| SCHEMBL31465366 | 0.81 | CDK2 (0.43) | PDE10ACCNT1CDK9PIK3CGPDE2A | |
| SCHEMBL31465470 | 0.81 | PDE10A (0.61) | PDE10ACCNT1CDK9PIK3CGPDE2A | |
| SCHEMBL16828091 | 0.74 | PDE10A (0.43) | PDE10ACCNT1CDK9CDK7CCNH | |
| SCHEMBL4102510 | 0.74 | PDE10A (0.43) | PDE10ACCNT1CDK9PIK3CGPDE2A | |
| SCHEMBL14545193 | 0.72 | CCNT1 (0.54) | CCNT1CDK9CDK7CCNHCDK4 | |
| SCHEMBL3338639 | 0.72 | PDE10A (0.33) | PDE10ACCNT1CDK9KCNN3 | |
| SCHEMBL7431490 | 0.70 | PRKAB2 (0.54) | PDE10ACCNT1CDK9CDK7CCNH | |
| SCHEMBL31728547 | 0.70 | PDE2A (0.40) | PDE10APDE2APDE3B | |
| SCHEMBL4253867 | 0.70 | PIM1 (0.56) | PDE10ACCNT1CDK9CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025068090-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2025-04-03 | — | — | WO | disclosed |