Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10376015 | 0.87 | CYP2D6 (0.67) | CYP2D6CYP3A4CYP2C19CYP1A2KMT2A | |
| SCHEMBL657896 | 0.87 | CYP2D6 (0.67) | CYP2D6CYP3A4CYP2C19CYP1A2KMT2A | |
| SCHEMBL26919229 | 0.86 | CYP2D6 (0.52) | CYP2D6CYP3A4CYP2C19CYP1A2KMT2A | |
| SCHEMBL31604801 | 0.86 | CYP2D6 (0.52) | CYP2D6CYP3A4CYP2C19CYP1A2KMT2A | |
| SCHEMBL26919234 | 0.86 | CYP2D6 (0.52) | CYP2D6CYP3A4CYP2C19CYP1A2KMT2A | |
| SCHEMBL4411239 | 0.86 | CYP3A4 (0.57) | CYP2D6CYP3A4CYP2C19CYP1A2KMT2A | |
| SCHEMBL10409067 | 0.86 | CYP2D6 (0.56) | CYP2D6CYP3A4CYP2C19CYP1A2KMT2A | |
| SCHEMBL4411763 | 0.86 | CYP3A4 (0.57) | CYP2D6CYP3A4CYP2C19CYP1A2KMT2A | |
| SCHEMBL3391969 | 0.86 | CYP3A4 (0.57) | CYP2D6CYP3A4CYP2C19CYP1A2KMT2A | |
| SCHEMBL13172107 | 0.85 | CYP2D6 (0.55) | CYP2D6CYP3A4CYP2C19CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049419-A1 | PYRAZOLYL COMPOUNDS AS EMOPAMIL BINDING PROTEIN INHIBITORS | GENZYME CORPORATION (US) | 2025-03-06 | — | — | WO | disclosed |