Sugi Predict

Sugi Predict / Compounds / SCHEMBL3391969

SCHEMBL3391969

SCHEMBL3391969

Cc1ccc(S(=O)(=O)OC2CCC(C(C)(C)C)CC2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 2/20 0.57
▸ CYP2C19 P33261 1/20 0.57
▸ CYP2D6 P10635 2/20 0.56
▸ CYP1A2 P05177 1/20 0.47
▸ MAPT P10636 1/20 0.38
▸ GAA P10253 1/20 0.37
▸ KMT2A Q03164 2/20 0.37
▸ SMN1; SMN2 Q16637 2/20 0.37
▸ ALDH1A1 P00352 4/20 0.36
▸ ACHE P22303 1/20 0.36
▸ TSHR P16473 1/20 0.36
▸ ALPL P05186 1/20 0.36
▸ CYP19A1 P11511 1/20 0.36
▸ ENPP3 O14638 2/20 0.36
▸ ENPP1 P22413 2/20 0.36
▸ HTR6 P50406 1/20 0.36
▸ ENPP2 Q13822 1/20 0.36
▸ AQP3 Q92482 1/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ VDR P11473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4411239 1.00 CYP3A4 (0.57) CYP3A4CYP2C19CYP2D6CYP1A2MAPT
SCHEMBL4411763 1.00 CYP3A4 (0.57) CYP3A4CYP2C19CYP2D6CYP1A2MAPT
SCHEMBL10409067 0.91 CYP2D6 (0.56) CYP3A4CYP2C19CYP2D6CYP1A2GAA
SCHEMBL10376015 0.88 CYP2D6 (0.67) CYP3A4CYP2C19CYP2D6CYP1A2GAA
SCHEMBL657896 0.88 CYP2D6 (0.67) CYP3A4CYP2C19CYP2D6CYP1A2GAA
SCHEMBL21024445 0.87 CYP2D6 (0.52) CYP3A4CYP2C19CYP2D6CYP1A2GAA
SCHEMBL31466151 0.86 CYP2D6 (0.55) CYP3A4CYP2C19CYP2D6CYP1A2GAA
SCHEMBL9100877 0.86 CYP3A4 (0.52) CYP3A4CYP2C19CYP2D6MAPTGAA
SCHEMBL8705300 0.85 CYP2D6 (0.51) CYP3A4CYP2C19CYP2D6CYP1A2MAPT
SCHEMBL8705296 0.85 CYP2D6 (0.51) CYP3A4CYP2C19CYP2D6CYP1A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130216723-A1 SULFONATE ESTERS AS LATENT ACID CATALYSTS KING INDUSTRIES (US) 2013-08-22 — — US claimed
EP-2203519-A1 SULFONATE ESTERS AS LATENT ACID CATALYSTS King Industries (US) 2010-07-07 — — EP claimed
US-20090104363-A1 Sulfonate esters as latent acid catalysts KING INDUSTRIES 2009-04-23 — — US claimed
WO-2009045466-A1 SULFONATE ESTERS AS LATENT ACID CATALYSTS KING INDUSTRIES (US) 2009-04-09 — — WO claimed
US-4454274-A Aminoplast curable coating compositions containing cycloaliphatic sulfonic acid esters as latent acid catalysts PPG INDUSTRIES, INC. (US) 1984-06-12 — — US claimed
US-20240417419-A1 C-TERMINAL HSP90 INHIBITORS UNIV KANSAS (US) 2024-12-19 — — US disclosed
EP-4403552-A2 C-TERMINAL HSP90-INHIBITORS The University of Kansas (US) 2024-07-24 — — EP disclosed
US-12024536-B2 C-terminal HSP90 inhibitors UNIVERSITY OF KANSAS (US) 2024-07-02 — — US disclosed
US-12024536-B2 C-terminal HSP90 inhibitors UNIVERSITY OF KANSAS (US) 2024-07-02 — — US disclosed
US-20230102047-A1 C-TERMINAL HSP90 INHIBITORS REATA PHARMACEUTICALS, INC. 2023-03-30 — — US disclosed
US-11450445-B2 Electroconductive film and method for manufacturing electroconductive pattern TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2022-09-20 — — US disclosed
US-11390640-B2 C-terminal Hsp90 inhibitors UNIVERSITY OF KANSAS (US) 2022-07-19 — — US disclosed
WO-2013119985-A1 C-TERMINAL HSP90 INHIBITORS UNIVERSITY OF KANSAS (US) 2013-08-15 — — WO disclosed
US-20090281332-A1 PROCESS FOR PRODUCING ESTER OR ALCOHOL MITSUI CHEMICALS, INC. (JP) 2009-11-12 — — US disclosed
EP-2039680-A1 PROCESS FOR PRODUCING ESTER OR ALCOHOL Mitsui Chemicals, Inc. (JP) 2009-03-25 — — EP disclosed
US-5877322-A Substituted pyridines, their preparation, and their use as pesticides and fungicides HOECHST SCHERING AGREVO GMBH (DE) 1999-03-02 — — US disclosed
US-5650417-A Substituted pyridines, their preparation, and their use as pesticides and fungicides HOECHST SCHERING AGREVO GMBH (DE) 1997-07-22 — — US disclosed
EP-0719255-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES Hoechst Schering AgrEvo GmbH (DE) 1996-07-03 — — EP disclosed
WO-1995007890-A1 SUBSTITUTED PYRIDINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS PESTICIDES AND FUNGICIDES HOECHST SCHERING AGREVO GMBH (DE) 1995-03-23 — — WO disclosed
US-4454274-A Aminoplast curable coating compositions containing cycloaliphatic sulfonic acid esters as latent acid catalysts PPG INDUSTRIES, INC. (US) 1984-06-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11390640-B2 C-terminal Hsp90 inhibitors HSP90AB2P, HSP90AB1, HSP90B1 CYP3A4 4878/4885CYP2C19 4871/4885CYP2D6 4702/4885
US-20230102047-A1 C-TERMINAL HSP90 INHIBITORS HSP90AB2P, HSP90AB1, HSP90B1 CYP3A4 4878/4885CYP2C19 4871/4885CYP2D6 4702/4885
US-20090281332-A1 PROCESS FOR PRODUCING ESTER OR ALCOHOL ADH5, ADH1A, ADH1C CYP3A4 22/4885CYP2C19 94/4885CYP2D6 149/4885
US-20090104363-A1 Sulfonate esters as latent acid catalysts ORAI1, SARAF, NAPA CYP3A4 3183/4885CYP2C19 3228/4885CYP2D6 4489/4885
US-20240417419-A1 C-TERMINAL HSP90 INHIBITORS HSP90AB2P, HSP90AB1, HSP90B1 CYP3A4 4878/4885CYP2C19 4871/4885CYP2D6 4702/4885
US-12024536-B2 C-terminal HSP90 inhibitors HSP90AB2P, HSP90AB1, HSP90B1 CYP3A4 4878/4885CYP2C19 4871/4885CYP2D6 4702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.