Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.48 |
| ▸ | CACNA2D2 | Q9NY47 | 3/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | KHK | P50053 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31466041 | 0.95 | PIM1 (0.47) | CACNA2D1CACNA2D2MCHR1HTR2CPIM1 | |
| Hydrochloric Acid SCHEMBL31466551 | 0.94 | PIM1 (0.46) | CACNA2D1CACNA2D2MCHR1HTR2CPIM1 | |
| SCHEMBL31466168 | 0.86 | MCHR1 (0.45) | CACNA2D1CACNA2D2MCHR1HTR2CPIM1 | |
| SCHEMBL31465938 | 0.84 | PIM1 (0.52) | CACNA2D1CACNA2D2PIM1SCN4ASCN9A | |
| SCHEMBL31466489 | 0.84 | PIM1 (0.61) | HTR2CPIM1SCN4ASCN9AHTR3A | |
| SCHEMBL31465901 | 0.83 | KHK (0.47) | CACNA2D1CACNA2D2MCHR1PIM1SCN4A | |
| SCHEMBL31466449 | 0.82 | PIM1 (0.44) | CACNA2D1CACNA2D2PIM1SCN4ASCN9A | |
| SCHEMBL31465847 | 0.81 | CNR1 (0.48) | CACNA2D1CACNA2D2MCHR1HTR2CPIM1 | |
| SCHEMBL31466055 | 0.81 | CACNA2D1 (0.45) | CACNA2D1CACNA2D2MCHR1HTR2C | |
| SCHEMBL31466148 | 0.80 | ADRB1 (0.60) | HTR2CPIM1CHRNB2CHRNA4KHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049419-A1 | PYRAZOLYL COMPOUNDS AS EMOPAMIL BINDING PROTEIN INHIBITORS | GENZYME CORPORATION (US) | 2025-03-06 | — | — | WO | disclosed |