SCHEMBL31466652

SCHEMBL31466652

O=C(NCCCCCCCCCCO)C(=O)c1c(-c2ccccc2)[nH]c2ccccc12

nearest known ligand 0.76

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.70
MAPT P10636 1/20 0.70
PAX8 Q06710 1/20 0.52
ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31466714 0.89 POLB (0.68) POLBMAPTPAX8ALDH1A1
SCHEMBL31252494 0.84 POLB (0.61) POLBMAPTPAX8ALDH1A1
SCHEMBL30791422 0.80 POLB (0.70) POLBMAPTPAX8ALDH1A1
SCHEMBL16146240 0.76 POLB (0.63) POLBMAPTPAX8ALDH1A1
SCHEMBL4669963 0.73 POLB (0.63) POLBMAPTPAX8ALDH1A1
SCHEMBL22204569 0.73 ALDH1A1 (0.63) POLBMAPTPAX8ALDH1A1
SCHEMBL30791409 0.73 ALDH1A1 (0.63) POLBMAPTPAX8ALDH1A1
SCHEMBL31252487 0.72 POLB (0.58) POLBMAPTPAX8ALDH1A1
SCHEMBL27202486 0.72 POLB (0.71) POLBMAPTALDH1A1
SCHEMBL28380663 0.72 ALDH1A1 (0.61) POLBMAPTPAX8ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775191-A Compounds for the treatment of diseases related to mitochondrial dysfunction 复旦大学 2025-04-08 CN disclosed