SCHEMBL31467218

O=C(NS(=O)(=O)c1ccc(NCC2CCOCC2)c([N+](=O)[O-])c1)c1ccc(N2CCC3(CC2)CN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C3)cc1Oc1cnc2[nH]ccc2c1

nearest known ligand 0.77

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	BCL2	P10415	20/20	0.77

▸	BCL2L1	Q07817	8/20	0.77

▸	NSD2	O96028	1/20	0.71

▸	ADORA3	P0DMS8	1/20	0.71

▸	CYP2C9	P11712	1/20	0.71

▸	ADRA2C	P18825	1/20	0.71

▸	SLC6A2	P23975	1/20	0.71

▸	BID	P55957	1/20	0.71

▸	SLC6A3	Q01959	1/20	0.71

▸	MCL1	Q07820	1/20	0.71

▸	ASPH	Q12797	1/20	0.71

▸	BCL2L2	Q92843	1/20	0.71

▸	BAD	Q92934	1/20	0.71

▸	NSD1	Q96L73	1/20	0.71

▸	NSD3	Q9BZ95	1/20	0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31467052	0.95	BCL2 (0.75)	BCL2BCL2L1NSD2ADORA3CYP2C9
SCHEMBL31467034	0.94	BCL2 (0.74)	BCL2BCL2L1NSD2ADORA3CYP2C9
SCHEMBL31467039	0.94	BCL2 (0.74)	BCL2BCL2L1NSD2ADORA3CYP2C9
SCHEMBL31467191	0.94	BCL2 (0.75)	BCL2BCL2L1NSD2ADORA3CYP2C9
SCHEMBL26669881	0.89	BCL2 (0.76)	BCL2BCL2L1
SCHEMBL31467013	0.88	BCL2 (0.77)	BCL2BCL2L1NSD2ADORA3CYP2C9
SCHEMBL31467232	0.88	BCL2 (0.76)	BCL2BCL2L1
SCHEMBL31467026	0.87	BCL2 (0.74)	BCL2BCL2L1NSD2ADORA3CYP2C9
SCHEMBL24774722	0.87	BCL2 (1.00)	BCL2BCL2L1CYP2C9
SCHEMBL30658633	0.87	BCL2 (1.00)	BCL2BCL2L1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2025064952-A1	BCL-2 INHIBITORS	Eil Therapeutics, Inc. (US)	2025-03-27	—	—	WO	disclosed