Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.50 |
| ▸ | KIT | P10721 | 3/20 | 0.49 |
| ▸ | SRC | P12931 | 6/20 | 0.46 |
| ▸ | ABL1 | P00519 | 5/20 | 0.46 |
| ▸ | ABL2 | P42684 | 5/20 | 0.46 |
| ▸ | EGFR | P00533 | 9/20 | 0.45 |
| ▸ | KDR | P35968 | 6/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.45 |
| ▸ | FLT1 | P17948 | 4/20 | 0.45 |
| ▸ | FLT4 | P35916 | 4/20 | 0.45 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.44 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | CIT | O14578 | 1/20 | 0.44 |
| ▸ | GAK | O14976 | 1/20 | 0.44 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | STK10 | O94804 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31467707 | 0.87 | EGFR (0.49) | PDPK1EHMT2KITSRCABL1 | |
| SCHEMBL5245086 | 0.78 | PDE10A (0.56) | — | |
| SCHEMBL8306125 | 0.75 | EHMT2 (0.53) | PDPK1EHMT2KITSRCABL1 | |
| SCHEMBL4417734 | 0.75 | EGFR (0.61) | PDPK1KITSRCABL1ABL2 | |
| SCHEMBL4687074 | 0.73 | KDR (0.60) | PDPK1KITSRCABL1ABL2 | |
| SCHEMBL19462030 | 0.72 | EHMT2 (0.53) | PDPK1EHMT2KITEGFRCHRM3 | |
| SCHEMBL19476946 | 0.72 | EHMT2 (0.53) | PDPK1EHMT2KITEGFRCHRM3 | |
| SCHEMBL19476947 | 0.72 | EHMT2 (0.53) | PDPK1EHMT2KITEGFRCHRM3 | |
| SCHEMBL30646062 | 0.71 | EGFR (0.44) | PDPK1KITEGFR | |
| SCHEMBL20303993 | 0.71 | KDR (0.50) | PDPK1EHMT2KITSRCABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025062157-A1 | NEW TREATMENTS FOR PAIN | SEVENLESS THERAPEUTICS LIMITED (GB) | 2025-03-27 | — | — | WO | disclosed |