SCHEMBL31467971

SCHEMBL31467971

CN1CCC(NCC2(C(F)(F)F)CC2)CC1

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 1/20 0.42
OPRL1 P41146 4/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
SLC6A5 Q9Y345 1/20 0.32
MITF O75030 1/20 0.31
NCF1 P14598 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25145686 0.75 DPP7 (0.39) DPP7
SCHEMBL16015436 0.72 DPP7 (0.44) DPP7OPRL1MEN1KMT2ASLC6A5
SCHEMBL20069054 0.71 DPP7 (0.41) DPP7MEN1KMT2AMITFNCF1
SCHEMBL17286003 0.71 DPP7 (0.42) DPP7OPRL1MEN1KMT2AMITF
SCHEMBL24204664 0.70 MEN1 (0.47) DPP7OPRL1MEN1KMT2AMITF
SCHEMBL19782058 0.69 DPP7 (0.41) DPP7OPRL1MEN1KMT2ASLC6A5
SCHEMBL21280986 0.69 DPP7 (0.39) DPP7MEN1KMT2AMITFNCF1
SCHEMBL17286044 0.69 DPP7 (0.42) DPP7MEN1KMT2AMITFNCF1
SCHEMBL31253537 0.67 KCNH2 (0.37)
SCHEMBL25105475 0.67 DPP7 (0.40) DPP7MEN1KMT2ANCF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115003655-B Cycloalkyl urea derivatives 住友制药株式会社 2025-03-21 CN disclosed