Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31253537 | 0.80 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL31467971 | 0.75 | DPP7 (0.42) | DPP7 | |
| SCHEMBL25944777 | 0.75 | GNAI3 (0.39) | GNAI3GNAO1GNAI1EPHX1 | |
| SCHEMBL31014257 | 0.75 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL25944873 | 0.71 | GNAI3 (0.43) | GNAI3GNAO1GNAI1 | |
| SCHEMBL13703407 | 0.71 | GNAI3 (0.43) | DPP7GNAI3GNAO1GNAI1KCNH2 | |
| SCHEMBL3652848 | 0.70 | GNAI3 (0.41) | DPP7GNAI3GNAO1GNAI1KCNH2 | |
| Hydrochloric Acid SCHEMBL3415583 | 0.68 | GNAI3 (0.44) | DPP7GNAI3GNAO1GNAI1KCNH2 | |
| SCHEMBL3411146 | 0.68 | GNAI3 (0.48) | DPP7GNAI3GNAO1GNAI1KCNH2 | |
| SCHEMBL17484497 | 0.68 | DPP7 (0.40) | DPP7GNAI3GNAO1GNAI1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023062049-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-04-20 | — | — | WO | disclosed |