SCHEMBL31468628

SCHEMBL31468628

C=C(c1ccccc1)c1ccc([Si](C)(C)CN(CC)CC)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
ALDH1A1 P00352 4/20 0.36
MAPT P10636 3/20 0.36
KDM4E B2RXH2 2/20 0.36
GRM2 Q14416 2/20 0.36
AGTR1 P30556 1/20 0.36
HPGD P15428 2/20 0.35
KCNH2 Q12809 3/20 0.33
ADRA2A P08913 3/20 0.33
NPSR1 Q6W5P4 2/20 0.33
EBP Q15125 2/20 0.33
SIGMAR1 Q99720 2/20 0.33
ESR1 P03372 2/20 0.33
CHRM2 P08172 2/20 0.33
ADORA3 P0DMS8 2/20 0.33
CHRM1 P11229 2/20 0.33
PTGS1 P23219 2/20 0.33
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31468622 0.85 MEN1 (0.41) KMT2AMEN1GRM2HPGDKCNH2
SCHEMBL31468659 0.84 MEN1 (0.51) KMT2AMEN1ALDH1A1MAPTKDM4E
SCHEMBL31468650 0.82 KMT2A (0.41) KMT2AMEN1MAPTKDM4EKCNH2
SCHEMBL31468476 0.81 KMT2A (0.41) KMT2AMEN1ALDH1A1MAPTKDM4E
SCHEMBL31468456 0.80 KMT2A (0.41) KMT2AMEN1ALDH1A1MAPTKDM4E
SCHEMBL16033382 0.78 MEN1 (0.47) KMT2AMEN1ALDH1A1MAPTKDM4E
SCHEMBL17444466 0.78 MEN1 (0.47) KMT2AMEN1ALDH1A1MAPTKDM4E
SCHEMBL31468632 0.76 NR1H2 (0.40) KMT2AMEN1GRM2HPGDNPSR1
SCHEMBL16033009 0.76 MEN1 (0.49) KMT2AMEN1ALDH1A1MAPTKDM4E
SCHEMBL16034157 0.74 MEN1 (0.47) KMT2AMEN1ALDH1A1MAPTGRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4541800-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME Shin-Etsu Chemical Co., Ltd. (JP) 2025-04-23 EP disclosed
US-20250122230-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122230-A1 NITROGEN-CONTAINING SILANE COMPOUND AND METHOD FOR PRODUCING SAME HRH3, HRH4, OR10J3 KMT2A 1539/4885MEN1 617/4885ALDH1A1 3683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.