SCHEMBL314687

SCHEMBL314687

CCC1=C(C)c2cc3[nH]c(cc4nc(cc5[nH]c(cc1n2)c(C)c5CCC(=O)O)C(CCC(=O)O)=C4C)c(C)c3CC

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.63
TDP1 Q9NUW8 3/20 0.63
MEN1 O00255 2/20 0.63
MAPT P10636 2/20 0.63
THRB P10828 2/20 0.63
MAPK1 P28482 2/20 0.63
KMT2A Q03164 2/20 0.63
APEX1 P27695 2/20 0.63
USP2 O75604 1/20 0.63
LMNA P02545 1/20 0.63
CYP1A2 P05177 1/20 0.63
POLB P06746 1/20 0.63
CYP2D6 P10635 1/20 0.63
HSPD1 P10809 1/20 0.63
CYP2C9 P11712 1/20 0.63
HPGD P15428 1/20 0.63
ALOX15 P16050 1/20 0.63
NFKB1 P19838 1/20 0.63
CYP2C19 P33261 1/20 0.63
RECQL P46063 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9609762 1.00 HSD17B10 (0.63) HSD17B10TDP1MEN1MAPTTHRB
SCHEMBL6413992 1.00 HSD17B10 (0.63) HSD17B10TDP1MEN1MAPTTHRB
SCHEMBL5447002 1.00 HSD17B10 (0.63) HSD17B10TDP1MEN1MAPTTHRB
SCHEMBL1603375 0.99 HSD17B10 (0.62) HSD17B10TDP1MEN1MAPTTHRB
SCHEMBL1603809 0.99 HSD17B10 (0.62) HSD17B10TDP1MEN1MAPTTHRB
SCHEMBL1602877 0.99 HSD17B10 (0.62) HSD17B10TDP1MEN1MAPTTHRB
SCHEMBL1603399 0.99 HSD17B10 (0.62) HSD17B10TDP1MEN1MAPTTHRB
SCHEMBL21051915 0.99 HSD17B10 (0.62) HSD17B10TDP1MEN1MAPTTHRB
SCHEMBL1603405 0.99 HSD17B10 (0.62) HSD17B10TDP1MEN1MAPTTHRB
SCHEMBL1603442 0.99 HSD17B10 (0.62) HSD17B10TDP1MEN1MAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2501 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025224101-A1 ANTI-VIRAL CONJUGATES FUNDACAO GIMM - GULBENKIAN INSTITUTE FOR MOLECULAR MEDICINE (PT) 2025-10-30 WO claimed
US-20250242033-A1 Novel Stannic Protoporfin Compositions, Methods of Making, and Uses Thereof RENIBUS THERAPEUTICS, INC. 2025-07-31 US claimed
US-20250161235-A1 STRESS TEST AND TREATMENT OF CHRONIC KIDNEY DISEASE RENIBUS THERAPEUTICS, INC. 2025-05-22 US claimed
US-12178789-B2 Stress test and treatment of chronic kidney disease RENIBUS THERAPEUTICS, INC. (US) 2024-12-31 US claimed
US-20240108589-A1 STRESS TEST AND TREATMENT OF CHRONIC KIDNEY DISEASE RENIBUS THERAPEUTICS, INC. 2024-04-04 US claimed
US-11883371-B2 Stress test and treatment of chronic kidney disease RENIBUS THERAPEUTICS, INC. (US) 2024-01-30 US claimed
CN-116144650-A Method for detecting content and/or activity of FTO and subfamily thereof 东南大学 2023-05-23 CN claimed
EP-4144379-A1 CONTRAST AGENT FILM-FORMING AGENT COMPOSITION, CONTRAST AGENT FILM-FORMING LIPID SOLUTION, AND CONTRAST AGENT AND PREPARATION METHOD THEREFOR Nanjing Transcend Vivoscope Bio-Technology Co., Ltd (CN) 2023-03-08 EP claimed
WO-2023013175-A1 CATIONIC POLYMER CONTAINING PORPHYRIN, TISSUE MARKING AGENT CONTAINING SAME, AND PHOTOSENSITIZER 国立研究開発法人物質・材料研究機構 2023-02-09 WO claimed
EP-4125860-A1 STRESS TEST AND TREATMENT OF CHRONIC KIDNEY DISEASE Renibus Therapeutics, Inc. (US) 2023-02-08 EP claimed
WO-1988004174-A1 USE OF TIN PROTOPORPHYRIN AND TIN MESOPORPHYRIN IN THE TREATMENT OF PSORIASIS THE ROCKEFELLER UNIVERSITY (US) 1988-06-16 WO claimed
US-4692440-A Therapeutic use of tin mesoporphyrin THE ROCKEFELLER UNIVERSITY (US) 1987-09-08 US claimed
US-4675338-A PEPTIDE LINKAGES WITH ASPARTIC AND GLUTAMIC ACID; ANTITUMOR A GENTS NIPPON PETROCHEMICALS CO., LTD. (JP) 1987-06-23 US claimed
US-4657902-A Therapeutic use of tin mesoporphyrin THE ROCKEFELLER UNIVERSITY (US) 1987-04-14 US claimed
EP-0213272-A2 New tetrapyrrole polyaminomonocarboxylic acid therapeutic agents Nippon Petrochemicals Co., Ltd. (JP) 1987-03-11 EP claimed
WO-1986005685-A1 THERAPEUTIC USE OF TIN MESOPORPHYRIN THE ROCKEFELLER UNIVERSITY (US) 1986-10-09 WO claimed
EP-0196079-A1 Therapeutic use of tin mesoporphyrin THE ROCKEFELLER UNIVERSITY (US) 1986-10-01 EP claimed
US-4610241-A Atherosclerosis treatment method GORDON, DAVID, SKOKIE, ILLINOIS 1986-09-09 US claimed
US-4590922-A INTRACELLULARLY LOCALIZING, THEN INDUCTINELY HEATING GORDON, DAVID, SKOKIE, ILLINOIS 1986-05-27 US claimed
EP-0168832-A2 Pharmaceutical composition containing a tetrapyrrole compound as active ingredient and process for the production of the tetrapyrrole compound Nippon Petrochemicals Co., Ltd. (JP) 1986-01-22 EP claimed