Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | APEX1 | P27695 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9118231 | 1.00 | HSD17B10 (0.62) | HSD17B10TDP1MEN1MAPTTHRB | |
| SCHEMBL5447002 | 0.99 | HSD17B10 (0.63) | HSD17B10TDP1MEN1MAPTTHRB | |
| SCHEMBL6413992 | 0.99 | HSD17B10 (0.63) | HSD17B10TDP1MEN1MAPTTHRB | |
| SCHEMBL9609762 | 0.99 | HSD17B10 (0.63) | HSD17B10TDP1MEN1MAPTTHRB | |
| SCHEMBL314687 | 0.99 | HSD17B10 (0.63) | HSD17B10TDP1MEN1MAPTTHRB | |
| SCHEMBL1603028 | 0.98 | HSD17B10 (0.62) | HSD17B10TDP1MEN1MAPTTHRB | |
| Hydrochloric Acid SCHEMBL1044825 | 0.98 | HSD17B10 (0.62) | HSD17B10TDP1MEN1MAPTTHRB | |
| SCHEMBL1603306 | 0.98 | HSD17B10 (0.62) | HSD17B10TDP1MEN1MAPTTHRB | |
| SCHEMBL1603497 | 0.98 | HSD17B10 (0.62) | HSD17B10TDP1MEN1MAPTTHRB | |
| SCHEMBL21051915 | 0.98 | HSD17B10 (0.62) | HSD17B10TDP1MEN1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995017893-A1 | METHODS FOR PREVENTING OR TREATING HIV-1 OR HIV-2 INFECTION | NEW YORK BLOOD CENTER (US) | 1995-07-06 | — | — | WO | claimed |
| US-6727240-B1 | PROTOPORPHYRIN IX IS VAGINALLY ADMINISTERED | NEW YORK BLOOD CENTER, INC. | 2004-04-27 | — | — | US | disclosed |
| US-6727240-B1 | PROTOPORPHYRIN IX IS VAGINALLY ADMINISTERED | NEW YORK BLOOD CENTER, INC. | 2004-04-27 | — | — | US | disclosed |
| WO-1995017893-A1 | METHODS FOR PREVENTING OR TREATING HIV-1 OR HIV-2 INFECTION | NEW YORK BLOOD CENTER (US) | 1995-07-06 | — | — | WO | disclosed |
| WO-1995017893-A1 | METHODS FOR PREVENTING OR TREATING HIV-1 OR HIV-2 INFECTION | NEW YORK BLOOD CENTER (US) | 1995-07-06 | — | — | WO | disclosed |