Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.62 |
| ▸ | IAPP | P10997 | 3/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3146887 | 1.00 | APP (0.62) | APPIAPPBACE1TOP2AHTR1A | |
| SCHEMBL8847657 | 0.81 | APP (0.66) | APPIAPPBACE1TOP2AHTR1A | |
| SCHEMBL8847664 | 0.81 | APP (0.66) | APPIAPPBACE1TOP2AHTR1A | |
| SCHEMBL23042776 | 0.79 | APP (0.68) | APPIAPPBACE1TOP2AHTR1A | |
| SCHEMBL3399806 | 0.78 | IAPP (0.65) | APPIAPPTRPA1POLB | |
| SCHEMBL3399802 | 0.78 | IAPP (0.65) | APPIAPPTRPA1POLB | |
| SCHEMBL547240 | 0.78 | APP (0.66) | APPIAPPHTR1A | |
| SCHEMBL17746768 | 0.78 | APP (0.66) | APPIAPPHTR1A | |
| SCHEMBL157815 | 0.78 | APP (0.66) | APPIAPPHTR1A | |
| SCHEMBL3398186 | 0.78 | APP (0.66) | APPIAPPHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152658-A2 | ORGANIC COMPOUNDS AND COMPOSITIONS HAVING THE ABILITY TO MODULATE FRAGRANCE COMPOSITIONS | Givaudan SA (CH) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008116338-A2 | ORGANIC COMPOUNDS AND COMPOSITIONS HAVING THE ABILITY TO MODULATE FRAGRANCE COMPOSITIONS | GIVAUDAN SA (CH) | 2008-10-02 | — | — | WO | disclosed |