Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.66 |
| ▸ | IAPP | P10997 | 4/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | POLA1 | P09884 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8847664 | 1.00 | APP (0.66) | APPIAPPHTR1ABACE1ESR1 | |
| SCHEMBL6940708 | 0.83 | APP (0.70) | APPIAPPHTR1ATOP2A | |
| SCHEMBL6940703 | 0.83 | APP (0.70) | APPIAPPHTR1ATOP2A | |
| SCHEMBL9681899 | 0.81 | APP (0.97) | APPIAPPHTR1ABACE1POLB | |
| SCHEMBL3146887 | 0.81 | APP (0.62) | APPIAPPHTR1ABACE1ESR1 | |
| SCHEMBL3146877 | 0.81 | APP (0.62) | APPIAPPHTR1ABACE1ESR1 | |
| SCHEMBL8847524 | 0.81 | APP (0.97) | APPIAPPHTR1ABACE1POLB | |
| SCHEMBL10825839 | 0.80 | APP (1.00) | APPIAPPHTR1ABACE1TOP2A | |
| SCHEMBL10826170 | 0.80 | APP (1.00) | APPIAPPHTR1ABACE1TOP2A | |
| SCHEMBL21133739 | 0.80 | APP (1.00) | APPIAPPHTR1ABACE1TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610169-A | Pharmaceutical Composition containing slightly water-soluble drug | THE GREEN CROSS CORPORATION (JP) | 1997-03-11 | — | — | US | disclosed |
| US-5462951-A | Dissolved in a polyoxyethylene sorbitan fatty acid ester and adsorbed onto a porosity inorganic substance | THE GREEN CROSS CORPORATION (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0448091-A2 | Pharmaceutical composition containing slightly water-soluble drug | THE GREEN CROSS CORPORATION (JP) | 1991-09-25 | — | — | EP | disclosed |