Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GGT1 | P19440 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4643007 | 0.82 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10HPGDHMGB1 | |
| SCHEMBL4645695 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDHMGB1 | |
| SCHEMBL29374906 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDHMGB1 | |
| SCHEMBL4644626 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDHMGB1 | |
| SCHEMBL219675 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDHMGB1 | |
| SCHEMBL2110850 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDHMGB1 | |
| SCHEMBL31336377 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10HPGDHMGB1 | |
| SCHEMBL282647 | 0.80 | KDM4E (0.58) | KDM4EALDH1A1HSD17B10HPGDHMGB1 | |
| SCHEMBL5511434 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDHMGB1 | |
| SCHEMBL3360162 | 0.78 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10HPGDHMGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759434-B2 | Ionically and/or organometallically functionalized silicone polymers crosslinkable to high-strength elastomers | WACKER CHEMIE AG (DE) | 2010-07-20 | — | — | US | disclosed |
| US-20080293878-A1 | Ionically and/or Organometallically Functionalized Silicone Polymers Crosslinkable to High-Strength Elastomers | WACKER CHEMIE AG (DE) | 2008-11-27 | — | — | US | disclosed |