SCHEMBL219675

SCHEMBL219675

O=C(O)c1ccccc1OC(F)(F)F

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.53
HSD17B10 Q99714 6/20 0.53
ALDH1A1 P00352 6/20 0.53
HPGD P15428 5/20 0.53
ESR1 P03372 1/20 0.53
ITGB3 P05106 1/20 0.53
ITGA2B P08514 1/20 0.53
HMGB1 P09429 1/20 0.53
TSHR P16473 1/20 0.53
GGT1 P19440 1/20 0.53
PTGS1 P23219 1/20 0.53
PTGS2 P35354 1/20 0.53
BLM P54132 1/20 0.53
NAPRT Q6XQN6 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
USP2 O75604 1/20 0.52
PDE3A Q14432 1/20 0.52
MAPT P10636 1/20 0.52
RXRA P19793 1/20 0.51
RXRB P28702 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29374906 1.00 KDM4E (0.53) KDM4EHSD17B10ALDH1A1HPGDESR1
SCHEMBL9588403 0.89 HTT (0.62) KDM4EHSD17B10ALDH1A1HPGDESR1
SCHEMBL5784212 0.86 ELANE (0.52) ALDH1A1RXRARXRBRXRGKCNK3
SCHEMBL240363 0.85 FABP4 (0.49) KDM4EHSD17B10ALDH1A1HPGDESR1
SCHEMBL4247156 0.85 KDM4E (0.50) KDM4EHSD17B10ALDH1A1HPGDESR1
SCHEMBL20516075 0.85 KDM4E (0.55) KDM4EHSD17B10ALDH1A1HPGDESR1
SCHEMBL6957926 0.84 KCNK3 (0.50) ALDH1A1RXRARXRBRXRGKCNK3
SCHEMBL16093747 0.83 RXRA (0.44) KDM4EHSD17B10ALDH1A1HPGDESR1
SCHEMBL1970631 0.83 ALB (0.52) KDM4EHSD17B10ALDH1A1HPGDESR1
SCHEMBL10937430 0.83 ELANE (0.57) ALDH1A1MAPTRXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 685 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118619869-B Halogen-containing lithium ion eutectic crystal and preparation method and application thereof 佛山大学 2024-11-22 CN claimed
CN-118619869-A Halogen-containing lithium ion eutectic crystal and preparation method and application thereof 佛山大学 2024-09-10 CN claimed
US-20240027903-A1 Resist Material And Patterning Process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-25 US claimed
EP-4288412-A1 MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME Rappta Therapeutics Oy (FI) 2023-12-13 EP claimed
CN-116120271-A Genipin derivative and preparation method and application thereof 广东工业大学 2023-05-16 CN claimed
EP-4065577-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES Bayer Aktiengesellschaft (DE) 2022-10-05 EP claimed
WO-2022167866-A1 MODULATORS OF PROTEIN PHOSPHATASE 2A (PP2A) AND METHODS USING SAME RAPPTA THERAPEUTICS OY (FI) 2022-08-11 WO claimed
WO-2021105091-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2021-06-03 WO claimed
CN-107406469-B For extracting C from aqueous streams1To C4Quaternary arylcarboxylate salt compositions of carboxylic acids 伊士曼化工公司 2021-04-30 CN claimed
EP-3390414-B1 QUATERNARY ARYLCARBOXYLATE COMPOSITIONS FOR EXTRACTING C1 TO C4 CARBOXYLIC ACIDS FROM AQUEOUS STREAMS EASTMAN CHEM CO (US) 2020-05-27 EP claimed
EP-3390414-A1 QUATERNARY ARYLCARBOXYLATE COMPOSITIONS FOR EXTRACTING C1 TO C4 CARBOXYLIC ACIDS FROM AQUEOUS STREAMS Eastman Chemical Company (US) 2018-10-24 EP claimed
US-20180198069-A1 P-Doping Cross-Linking Of Organic Hole Transporters SIEMENS AKTIENGESELLSCHAFT (DE) 2018-07-12 US claimed
EP-3057151-B1 BISMUTH AND TIN COMPLEXES AS P DOTANDS FOR ORGANIC ELECTRONIC MATRIX MATERIALS SIEMENS AG (DE) 2018-01-31 EP claimed
WO-2017105476-A1 QUATERNARY ARYLCARBOXYLATE COMPOSITIONS FOR EXTRACTING C1 TO C4 CARBOXYLIC ACIDS FROM AQUEOUS STREAMS EASTMAN CHEMICAL COMPANY (US) 2017-06-22 WO claimed
US-20170098787-A1 MAIN GROUP METAL COMPLEXES AS P-DOPANTS FOR ORGANIC ELECTRONIC MATRIX MATERIALS SIEMENS AKTIENGESELLSCHAFT (DE) 2017-04-06 US claimed
US-9611209-B1 Quaternary arylcarboxylate compositions for extracting C1 to C4 carboxylic acids from aqueous streams EASTMAN CHEMICAL COMPANY (US) 2017-04-04 US claimed
EP-3057151-A1 PRINCIPAL GROUP METAL COMPLEXES AS P DOTANDS FOR ORGANIC ELECTRONIC MATRIX MATERIALS Siemens Aktiengesellschaft (DE) 2016-08-17 EP claimed
EP-2379558-B1 NOVEL HETEROCYCLIC COMPOUNDS FOR USE AS METAP-2 INHIBITORS MERCK PATENT GMBH (DE) 2016-03-23 EP claimed
WO-2010129848-A2 2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXAMIDES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-11-11 WO claimed
US-5219477-A Containing organometallic salts and inorganic metal borates; fromo reactinmetal hydroxide with phenols or aromatic carboxylic acid THE DOW CHEMICAL COMPANY (US) 1993-06-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170098787-A1 MAIN GROUP METAL COMPLEXES AS P-DOPANTS FOR ORGANIC ELECTRONIC MATRIX MATERIALS SCO2, SOD3, NCOA3 KDM4E 1107/4885HSD17B10 2065/4885ALDH1A1 1949/4885
US-20240027903-A1 Resist Material And Patterning Process LBR, HNRNPU, EWSR1 KDM4E 778/4885HSD17B10 3657/4885ALDH1A1 4741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.