Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765502 | 0.82 | MAPT (0.59) | MAPTCYP1A2CYP3A4CYP2C19CNR2 | |
| SCHEMBL765097 | 0.78 | MAPT (0.52) | MAPTCYP1A2CYP3A4CYP2C19CNR2 | |
| SCHEMBL10207104 | 0.78 | MAPT (0.55) | MAPTCYP1A2CYP3A4CYP2C19CNR2 | |
| SCHEMBL14314439 | 0.77 | L3MBTL1 (0.58) | MAPTCNR2CNR1PPARGALDH1A1 | |
| SCHEMBL10289883 | 0.77 | MAPT (0.53) | MAPTCYP1A2CYP3A4CYP2C19CNR2 | |
| SCHEMBL13492012 | 0.77 | MAPT (0.53) | MAPTCYP1A2CYP3A4CYP2C19CNR2 | |
| SCHEMBL14533977 | 0.76 | MAPT (0.49) | MAPTCYP1A2CYP3A4CYP2C19CNR2 | |
| SCHEMBL10289787 | 0.75 | MAPT (0.48) | MAPTCYP1A2CYP3A4CYP2C19CNR2 | |
| SCHEMBL2850890 | 0.75 | HTT (0.45) | MAPTTSHRALDH1A1KDM4EHPGD | |
| SCHEMBL13064843 | 0.74 | APP (0.41) | TTRALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119684313-A | Macrocyclic compound and preparation method and application thereof | 上海爱科百发生物医药技术股份有限公司 | 2025-03-25 | — | — | CN | disclosed |