Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 4/20 | 0.33 |
| ▸ | EEF2K | O00418 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.31 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10267839 | 0.75 | KDM4E (0.33) | — | |
| SCHEMBL15024227 | 0.65 | HTR2C (0.46) | ADORA2A | |
| SCHEMBL9433906 | 0.61 | LIMK1 (0.46) | LIMK1EEF2KPI4KAPI4K2BPI4K2A | |
| SCHEMBL361602 | 0.61 | LIMK1 (0.46) | LIMK1EEF2KDYRK1A | |
| SCHEMBL12167769 | 0.60 | LIMK1 (0.33) | LIMK1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL12481992 | 0.58 | PDE4A (0.35) | PDGFRB | |
| SCHEMBL9911123 | 0.58 | PDE11A (0.36) | — | |
| SCHEMBL18095871 | 0.57 | LIMK1 (0.32) | LIMK1 | |
| SCHEMBL4195565 | 0.57 | DYRK1A (0.35) | LIMK1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL20416988 | 0.57 | SMN1; SMN2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119684313-A | Macrocyclic compound and preparation method and application thereof | 上海爱科百发生物医药技术股份有限公司 | 2025-03-25 | — | — | CN | disclosed |