Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | ERBB4 | Q15303 | 4/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31469237 | 0.87 | TSHR (0.40) | ALDH1A1GAALMNAUSP2EGFR | |
| SCHEMBL31469378 | 0.84 | ATR (0.47) | ALDH1A1GAATSHR | |
| SCHEMBL31469324 | 0.78 | ATR (0.40) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31469333 | 0.77 | EGFR (0.43) | ALDH1A1GAAEGFRMALT1ERBB4 | |
| SCHEMBL31469351 | 0.77 | GSK3B (0.46) | ALDH1A1GAAEGFRGSK3BERBB4 | |
| SCHEMBL26110729 | 0.77 | EGFR (0.48) | EGFRERBB4ERBB2 | |
| SCHEMBL26113555 | 0.76 | EGFR (0.48) | ALDH1A1GAAEGFRMAPTMALT1 | |
| SCHEMBL26586326 | 0.74 | EGFR (0.50) | ALDH1A1EGFRERBB4ERBB2 | |
| SCHEMBL26584629 | 0.73 | HTT (0.51) | ALDH1A1GAAHTTLMNAEGFR | |
| SCHEMBL26111167 | 0.72 | EGFR (0.43) | ALDH1A1GAAHTTEGFRERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122029158-A | EGFR inhibitors | 缆图药品公司 | 2026-05-12 | — | — | CN | disclosed |
| WO-2025080784-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2025-04-17 | — | — | WO | disclosed |