Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | STK17B | O94768 | 2/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.35 |
| ▸ | DAPK2 | Q9UIK4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31469256 | 0.87 | ALDH1A1 (0.44) | TSHRALDH1A1EGFRGAAKDM4E | |
| SCHEMBL31469378 | 0.85 | ATR (0.47) | TSHRALDH1A1GAA | |
| SCHEMBL26114206 | 0.70 | TSHR (0.53) | TSHREGFRKDM4EERBB2CYP3A4 | |
| SCHEMBL26110729 | 0.68 | EGFR (0.48) | EGFRERBB2 | |
| SCHEMBL31469324 | 0.66 | ATR (0.40) | RAB9A | |
| SCHEMBL31469333 | 0.66 | EGFR (0.43) | ALDH1A1EGFRGAAKDM4EERBB2 | |
| SCHEMBL26113555 | 0.66 | EGFR (0.48) | ALDH1A1EGFRGAAKDM4EERBB2 | |
| SCHEMBL31469351 | 0.66 | GSK3B (0.46) | ALDH1A1EGFRGAAKDM4EERBB2 | |
| SCHEMBL31469356 | 0.66 | MAPT (0.44) | EGFRKDM4EKMT2AMEN1ERBB2 | |
| SCHEMBL21248316 | 0.64 | ALDH1A1 (0.40) | ALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122029158-A | EGFR inhibitors | 缆图药品公司 | 2026-05-12 | — | — | CN | disclosed |
| WO-2025080784-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2025-04-17 | — | — | WO | disclosed |