Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 15/20 | 0.41 |
| ▸ | HTR2C | P28335 | 15/20 | 0.41 |
| ▸ | HTR2B | P41595 | 7/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.40 |
| ▸ | PDE9A | O76083 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31469637 | 0.84 | MCHR1 (0.38) | HTR2AHTR2CHTR2BHTR1AADRA2A | |
| SCHEMBL31469669 | 0.83 | HTR2A (0.43) | HTR2AHTR2CHTR2BHTR1AADRA2A | |
| SCHEMBL31406228 | 0.78 | ADORA3 (0.39) | HTR2AHTR2CHTR2B | |
| SCHEMBL22494315 | 0.77 | HTR2A (0.37) | HTR2AHTR2CHTR2BHTR1AADRA2A | |
| SCHEMBL31018649 | 0.74 | HTR2A (0.33) | HTR2AHTR2CHTR2BHTR1AADRA2A | |
| SCHEMBL31469628 | 0.74 | SRC (0.39) | PDE9A | |
| SCHEMBL18926932 | 0.73 | KDM4E (0.46) | HTR2AHTR2CHTR2BPDE9A | |
| SCHEMBL31469629 | 0.72 | ADORA2A (0.40) | — | |
| SCHEMBL31018622 | 0.72 | HTR2A (0.31) | HTR2AHTR2CHTR2B | |
| SCHEMBL31018708 | 0.71 | BACE1 (0.32) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025079989-A1 | PYRAZOLO[3,4-B]PYRIDINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사유한양행 | 2025-04-17 | — | — | WO | disclosed |