Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21014315 | 0.80 | ESR1 (0.46) | ESR1ESR2TSHRL3MBTL1MAPK1 | |
| SCHEMBL18264342 | 0.78 | TSHR (0.40) | ESR1ESR2TSHRL3MBTL1MAPK1 | |
| SCHEMBL19464637 | 0.78 | MAPT (0.42) | ESR1ESR2TSHRL3MBTL1MAPK1 | |
| SCHEMBL13677282 | 0.78 | MAPT (0.42) | ESR1ESR2TSHRL3MBTL1MAPK1 | |
| SCHEMBL18264361 | 0.78 | TSHR (0.40) | ESR1ESR2TSHRL3MBTL1MAPK1 | |
| SCHEMBL13104799 | 0.78 | MAPT (0.42) | ESR1ESR2TSHRL3MBTL1MAPK1 | |
| SCHEMBL30328253 | 0.78 | FDPS (0.37) | L3MBTL1MAPK1S1PR3S1PR1PTK2 | |
| SCHEMBL1791801 | 0.78 | FDPS (0.37) | L3MBTL1MAPK1S1PR3S1PR1PTK2 | |
| SCHEMBL31469780 | 0.77 | S1PR3 (0.32) | S1PR3S1PR1 | |
| SCHEMBL23126409 | 0.74 | CHRM2 (0.47) | ESR1ESR2TSHRL3MBTL1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025030002-A2 | DGK TARGETING COMPOUNDS AND USES THEREOF | ARVINAS OPERATIONS, INC. (US) | 2025-02-06 | — | — | WO | disclosed |