Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | TOP1 | P11387 | 2/20 | 0.42 |
| ▸ | HRAS | P01112 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.39 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27197324 | 0.95 | HDAC1 (0.55) | HDAC1HDAC2HDAC8TOP1HRAS | |
| SCHEMBL13845563 | 0.92 | HDAC1 (0.49) | HDAC1HDAC2HDAC8TOP1HRAS | |
| SCHEMBL24510762 | 0.90 | HDAC1 (0.48) | HDAC1HDAC2HDAC8TOP1HRAS | |
| SCHEMBL31614482 | 0.90 | TOP1 (0.51) | HDAC1HDAC2HDAC8TOP1HRAS | |
| SCHEMBL30125564 | 0.89 | HDAC1 (0.50) | HDAC1HDAC2HDAC8TOP1HRAS | |
| SCHEMBL23744959 | 0.89 | HDAC1 (0.55) | HDAC1HDAC2HDAC8TOP1HRAS | |
| SCHEMBL23745098 | 0.89 | HDAC1 (0.55) | HDAC1HDAC2HDAC8TOP1HRAS | |
| SCHEMBL23745126 | 0.89 | HDAC1 (0.55) | HDAC1HDAC2HDAC8TOP1HRAS | |
| SCHEMBL13845730 | 0.89 | HDAC1 (0.55) | HDAC1HDAC2HDAC8TOP1HRAS | |
| SCHEMBL31469819 | 0.88 | HDAC1 (0.47) | HDAC1HDAC2HDAC8TOP1HRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076181-A1 | METHODS AND COMPOUNDS FOR MODULATING HUNTINGTON'S DISEASE | Design Therapeutics, Inc. (US) | 2025-04-10 | — | — | WO | disclosed |