SCHEMBL31470148

SCHEMBL31470148

[C-]#[N+]c1ccc(C(=O)OCC(=O)Nc2cccc(Cl)c2Cl)cc1

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.66
LMNA P02545 3/20 0.66
ALDH1A1 P00352 5/20 0.57
KMT2A Q03164 4/20 0.53
MAPT P10636 3/20 0.53
MEN1 O00255 3/20 0.52
SFN P31947 1/20 0.52
TDP1 Q9NUW8 3/20 0.49
NPY1R P25929 1/20 0.47
NPY2R P49146 1/20 0.47
POLB P06746 3/20 0.46
MAPK1 P28482 2/20 0.45
RXFP1 Q9HBX9 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31470150 0.90 KMT2A (0.65) L3MBTL1LMNAALDH1A1KMT2AMAPT
SCHEMBL31470178 0.81 BLM (0.61) LMNAALDH1A1KMT2AMAPTMEN1
SCHEMBL31470181 0.81 ALDH1A1 (0.57) LMNAALDH1A1KMT2AMAPTMEN1
SCHEMBL31470183 0.81 SMN1; SMN2 (0.59) L3MBTL1LMNAALDH1A1KMT2AMAPT
SCHEMBL31470156 0.80 ALDH1A1 (0.50) L3MBTL1LMNAALDH1A1KMT2AMAPT
SCHEMBL31470186 0.79 SMN1; SMN2 (0.60) L3MBTL1LMNAALDH1A1KMT2AMAPT
SCHEMBL31470152 0.79 MEN1 (0.69) ALDH1A1KMT2AMAPTMEN1MAPK1
SCHEMBL31470187 0.78 HTT (0.61) L3MBTL1LMNAALDH1A1KMT2AMAPT
SCHEMBL31470167 0.78 MEN1 (0.71) L3MBTL1LMNAALDH1A1KMT2AMAPT
SCHEMBL31470192 0.77 KDM4E (0.55) LMNAALDH1A1KMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025027448-A1 ANTIBACTERIAL AGENTS, COMPOSITIONS AND USES THEREOF Università Degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT) 2025-02-06 WO claimed
WO-2025027448-A1 ANTIBACTERIAL AGENTS, COMPOSITIONS AND USES THEREOF Università Degli Studi del Piemonte Orientale “Amedeo Avogadro” (IT) 2025-02-06 WO disclosed