Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 15/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38662683 | 1.00 | CRBN (0.42) | CRBNDDB1HRH3 | |
| SCHEMBL30112356 | 0.88 | CRBN (0.41) | CRBNDDB1 | |
| SCHEMBL29197791 | 0.88 | CRBN (0.41) | CRBNDDB1 | |
| SCHEMBL24881500 | 0.87 | CRBN (0.37) | CRBNDDB1 | |
| SCHEMBL30888811 | 0.87 | CRBN (0.37) | CRBNDDB1 | |
| SCHEMBL29197732 | 0.86 | CRBN (0.43) | CRBNDDB1 | |
| SCHEMBL23538602 | 0.85 | CRBN (0.50) | CRBNDDB1HRH3 | |
| SCHEMBL29744853 | 0.85 | CRBN (0.50) | CRBNDDB1HRH3 | |
| SCHEMBL24880882 | 0.85 | POLB (0.34) | CRBNDDB1 | |
| SCHEMBL23538810 | 0.84 | CRBN (0.51) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025077891-A1 | DEGRADATION AGENT COMPOUND TARGETING IRAK4, AND USE THEREOF | 江苏先声药业有限公司 | 2025-04-17 | — | — | WO | disclosed |