Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 14/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 12/20 | 0.34 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 4/20 | 0.32 |
| ▸ | LCAT | P04180 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24881500 | 0.89 | CRBN (0.37) | CRBNDDB1GSPT1LCAT | |
| SCHEMBL30888811 | 0.89 | CRBN (0.37) | CRBNDDB1GSPT1LCAT | |
| SCHEMBL24880619 | 0.86 | POLB (0.34) | POLBCRBNDDB1GSPT1ACACB | |
| SCHEMBL24880878 | 0.85 | POLB (0.35) | POLBCRBNDDB1GSPT1ACACB | |
| SCHEMBL31470588 | 0.85 | CRBN (0.42) | CRBNDDB1 | |
| SCHEMBL38662683 | 0.85 | CRBN (0.42) | CRBNDDB1 | |
| SCHEMBL29197721 | 0.85 | CRBN (0.39) | CRBNDDB1LCAT | |
| SCHEMBL30112356 | 0.80 | CRBN (0.41) | CRBNDDB1GSPT1 | |
| SCHEMBL29197791 | 0.80 | CRBN (0.41) | CRBNDDB1GSPT1 | |
| SCHEMBL24880609 | 0.80 | POLB (0.36) | POLBCRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283610-A1 | COMPOUNDS FOR TARGETING DEGRADATION OF IRAK4 PROTEINS | BIOGEN MA INC. (US) | 2023-01-12 | — | — | WO | disclosed |