Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 11/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1011199 | 0.94 | ALK (0.31) | ALK | |
| SCHEMBL3146162 | 0.93 | TDP1 (0.30) | — | |
| SCHEMBL3150903 | 0.90 | ALK (0.36) | ALK | |
| SCHEMBL25602026 | 0.88 | MDM2 (0.32) | ALK | |
| SCHEMBL1009178 | 0.87 | ALK (0.33) | ALK | |
| SCHEMBL3151411 | 0.87 | — | — | |
| SCHEMBL25665502 | 0.86 | MEN1 (0.35) | ALK | |
| SCHEMBL25714230 | 0.85 | ALK (0.35) | ALK | |
| SCHEMBL25602145 | 0.85 | ALK (0.40) | ALK | |
| SCHEMBL25602258 | 0.84 | ALK (0.43) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963896-B1 | PHOTOCHROMIC MATERIALS HAVING ELECTRON-WITHDRAWING SUBSTITUENTS | TRANSITIONS OPTICAL INC (US) | 2010-02-10 | — | — | EP | claimed |
| US-7556751-B2 | Photochromic materials having electron-withdrawing substituents | TRANSITIONS OPTICAL, INC. (US) | 2009-07-07 | — | — | US | claimed |
| US-20070138449-A1 | Photochromic materials having electron-withdrawing substituents | TRANSITIONS OPTICAL LIMITED (IE) | 2007-06-21 | — | — | US | claimed |
| EP-3331581-B1 | MECHANOPHORIC MEDICAL PRODUKT | AESCULAP AG (DE) | 2020-07-08 | — | — | EP | disclosed |
| EP-1963896-B1 | PHOTOCHROMIC MATERIALS HAVING ELECTRON-WITHDRAWING SUBSTITUENTS | TRANSITIONS OPTICAL INC (US) | 2010-02-10 | — | — | EP | disclosed |
| US-7556751-B2 | Photochromic materials having electron-withdrawing substituents | TRANSITIONS OPTICAL, INC. (US) | 2009-07-07 | — | — | US | disclosed |
| US-20070138449-A1 | Photochromic materials having electron-withdrawing substituents | TRANSITIONS OPTICAL LIMITED (IE) | 2007-06-21 | — | — | US | disclosed |